Preimplantation Genetic Testing (PGT) in Vietnam

• Preimplantation Genetic Testing (PGT) is an advanced genetic screening technique used in conjunction with in vitro fertilization (IVF) to identify genetic or chromosomal abnormalities in embryos before pregnancy. As global awareness of genetic health increases, more couples are seeking PGT to improve IVF success rates and reduce the risk of inherited conditions.

  In recent years, Vietnam has emerged as a competitive destination for Preimplantation Genetic Testing, offering modern IVF laboratories, internationally trained fertility specialists, and significantly lower costs compared to Western countries. This article provides a comprehensive overview of PGT in Vietnam, including how it works, available testing types, accuracy, costs, legal considerations, and why international patients are choosing Vietnam for genetic screening during IVF.

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  What Is Preimplantation Genetic Testing (PGT)?

  Preimplantation Genetic Testing (PGT) is a laboratory technique used to analyze embryos created through IVF before they are transferred to the uterus. The purpose of PGT is to ensure that only embryos with the correct number of chromosomes or without specific genetic disorders are selected for transfer.

  PGT does not alter or modify embryos. Instead, it provides valuable genetic information that helps doctors and patients make informed decisions during fertility treatment.

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  Why Is PGT Used in IVF?

  PGT is commonly recommended to:

  • Improve IVF success rates

  • Reduce the risk of miscarriage

  • Prevent the transmission of inherited genetic disorders

  • Select embryos with the highest implantation potential

  • Reduce the likelihood of chromosomal abnormalities such as Down syndrome

  PGT is especially beneficial for couples with known genetic risks or repeated IVF failure.

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  Types of Preimplantation Genetic Testing Available in Vietnam

  Vietnamese fertility centers offer all major types of PGT, performed in modern embryology laboratories using advanced genetic technologies.

  PGT-A (Preimplantation Genetic Testing for Aneuploidy)

  PGT-A screens embryos for chromosomal abnormalities, such as extra or missing chromosomes. It is commonly recommended for:

  • Women aged 35 and older

  • Patients with recurrent miscarriage

  • Repeated IVF implantation failure

  • Severe male factor infertility

  PGT-A helps identify chromosomally normal embryos, increasing the chance of a healthy pregnancy.

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  PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)

  PGT-M is used to detect specific inherited genetic conditions caused by mutations in a single gene. Examples include:

  • Thalassemia

  • Cystic fibrosis

  • Sickle cell anemia

  • Huntington’s disease

  • Hemophilia

  This type of testing is recommended for couples who are carriers of known genetic disorders.

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  PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)

  PGT-SR is designed for individuals with chromosomal structural abnormalities, such as balanced translocations or inversions. These abnormalities may not affect the individual’s health but can lead to miscarriage or infertility.

  PGT-SR helps select embryos with balanced or normal chromosomal structures.

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  How Preimplantation Genetic Testing Works

  PGT is performed as part of the IVF process and follows these key steps:

  1. Ovarian stimulation and egg retrieval

  2. Fertilization using IVF or ICSI

  3. Embryo development to the blastocyst stage (day 5 or 6)

  4. Embryo biopsy, where a few cells are carefully removed from the embryo

  5. Genetic analysis of the biopsied cells in a specialized laboratory

  6. Embryo freezing (vitrification) while awaiting test results

  7. Transfer of genetically suitable embryos in a later cycle

  The biopsy process is considered safe and does not damage embryo development when performed by experienced embryologists.

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  Accuracy and Reliability of PGT

  PGT is highly accurate when performed in accredited laboratories using advanced genetic sequencing methods.

  • Accuracy rates are typically 95–99%, depending on the testing type

  • False positives and negatives are rare but possible

  • Mosaic embryos may require additional clinical interpretation

  Vietnamese IVF centers collaborate with certified genetic laboratories and follow international quality standards to ensure reliable results.

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  Who Is a Good Candidate for PGT?

  PGT may be recommended for:

  • Women aged 35 or older

  • Couples with a family history of genetic disorders

  • Carriers of inherited genetic conditions

  • Couples with recurrent miscarriage

  • Patients with multiple failed IVF cycles

  • Couples seeking to reduce genetic risks

  A fertility specialist will evaluate each case individually before recommending PGT.

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  Is PGT Mandatory in IVF?

  PGT is optional and not required for all IVF patients. Many couples conceive successfully without genetic testing. However, PGT can significantly improve outcomes for high-risk patients.

  Doctors in Vietnam emphasize personalized treatment planning rather than routine testing for all patients.

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  Cost of Preimplantation Genetic Testing in Vietnam

  One of the main reasons international patients choose Vietnam for PGT is affordability.

  Average Cost Estimates

  • PGT-A: USD 2,000 – 3,500

  • PGT-M / PGT-SR: USD 3,000 – 5,000

  • IVF + PGT package: USD 6,000 – 10,000 (depending on complexity)

  These prices are substantially lower than in countries such as the United States, Australia, or Western Europe, where PGT costs can exceed USD 5,000–8,000 alone.

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  What Is Included in PGT Packages?

  Most fertility centers in Vietnam include:

  • Fertility specialist consultation

  • IVF laboratory procedures

  • Embryo biopsy and freezing

  • Genetic testing and reporting

  • Follow-up consultation to explain results

  Medical tourism coordinators may also assist with travel, accommodation, and language support.

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  Legal and Ethical Considerations in Vietnam

  PGT is legal and regulated in Vietnam and must comply with national healthcare regulations.

  Important considerations include:

  • PGT is permitted for medical indications

  • Sex selection for non-medical reasons is prohibited

  • Informed consent is required

  • Genetic counseling is strongly recommended

  Vietnamese clinics follow ethical standards aligned with international reproductive medicine guidelines.

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  How Long Does PGT Take?

  The genetic testing process typically takes 1–3 weeks, depending on the testing type and laboratory workflow. Embryos are safely frozen during this period and transferred in a subsequent cycle.

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  PGT and Embryo Freezing

  Most PGT cycles involve frozen embryo transfer (FET) rather than fresh transfer. This approach allows time for genetic analysis and improves uterine receptivity, leading to higher pregnancy rates.

  Vietnamese fertility clinics are experienced in vitrification techniques with excellent embryo survival rates.

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  PGT vs Prenatal Genetic Testing

  Aspect	PGT	Prenatal Testing
  Timing	Before pregnancy	During pregnancy
  Risk	No risk to pregnancy	May involve invasive procedures
  Purpose	Embryo selection	Fetal diagnosis
  Decision stage	Before implantation	After conception

  PGT allows couples to make informed decisions before pregnancy begins.

“Preimplantation Genetic Testing (PGT) in Vietnam: Advanced screening to ensure healthy embryos during IVF, enhancing success rates and reducing hereditary risks.”

Why Choose Vietnam for PGT?

Why Choose Vietnam for PGT?

Vietnam offers several advantages for international patients seeking genetic testing during IVF:

Advanced IVF Laboratories

Fertility centers are equipped with modern embryology labs and genetic testing technologies.

Experienced Specialists

Vietnamese fertility doctors and embryologists receive international training and perform high volumes of IVF and PGT cycles.

Affordable Costs

High-quality care at a fraction of Western prices.

Short Waiting Times

Treatment can often begin within weeks.

Comprehensive International Patient Support

Clinics and medical tourism providers offer assistance with appointments, interpretation, and logistics.

Best Cities for PGT in Vietnam

• Ho Chi Minh City – Leading IVF centers and international hospitals

• Hanoi – Academic fertility institutes and public–private centers

• Da Nang – Growing fertility services with modern facilities

Preparing for PGT in Vietnam

Before traveling, patients are advised to:

• Share detailed medical and genetic history

• Complete preliminary tests at home if possible

• Discuss expectations and limitations of PGT

• Plan sufficient time for treatment and follow-up

Many clinics offer online consultations before arrival.

Frequently Asked Questions

Does PGT guarantee a healthy baby?
No test can guarantee a healthy baby, but PGT significantly reduces genetic risks.

Can mosaic embryos be transferred?
In some cases, mosaic embryos may still result in healthy pregnancies, under specialist guidance.

Is PGT safe for embryos?
Yes, when performed by experienced embryologists using modern techniques.

Can PGT be used for gender selection?
Sex selection is allowed only for medical reasons in Vietnam.

Final Thoughts

Preimplantation Genetic Testing (PGT) in Vietnam offers a safe, accurate, and affordable solution for couples seeking to reduce genetic risks and improve IVF success. With modern laboratories, experienced specialists, and patient-centered care, Vietnam has become a trusted destination for advanced fertility treatment.

For international patients seeking high-quality genetic screening combined with cost-effective IVF care, Vietnam stands out as a reliable and ethical choice for PGT, providing both medical excellence and compassionate support throughout the fertility journey.